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All About Anti thrombin Antibodies

Anti-thrombin antibodies are autoantibodies that target against thrombin, which could constitute some of the anticoagulants used in lupus and may be observed in higher levels in systemic lupus. You can know more about thrombin antibodies via

Anti-thrombin antibodies - Wikipedia

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The mammal typically has an anti-thrombin function (antithrombin III) that is distinct from autoimmune anti-thrombin. In the antithrombin-thrombin complex, antithrombin antibodies can bind to both forms of thrombin.

Antibodies (IgG) against thrombin can significantly reduce its activity. Anti-thrombin inhibitory antibodies are classified into two types: those that inhibit coagulation activity only and those that inhibit both coagulation and amidase activity.

Antithrombin III binding to thrombin was similarly inhibited by autoimmune antithrombin. These activities are more common in people with primary biliary cirrhosis. 

Thrombin Antibody is an anti-mouse monoclonal IgG1 k that has been mentioned in eight publications. It is available at 200 Ug/ml. It is specific to an epitope mapping of amino acids 331-376 inside an inner region Thrombin with human origin.

Anti-Thrombin Antibody (F-1) is suggested to detect Prothrombin precursors and mature chains and Thrombin LC of mice, rats, and humans of origin using the WB method, IP, IF, IHC(P), and the ELISA.

Anti-Thrombin Antibody (F-1) can be as a conjugate to agarose, which is used to treat IP, HRP to treat WB IHC(P) along with ELISA as well as to the phycoerythrin, or FITC, for IHC(P), IHC(P) and FCM.